Conditions
Hypoactive Sexual Desire Disorder
News

Could Testosterone Therapy Be a Key to Weight Loss?

Overweight/Obese Women Likely to Have Sexual Difficulties

New Details on Oral Testosterone

Sexual Issues Need Attention in Female Childhood Cancer Survivors

Taking Testosterone? Watch for Polycythemia and Sleep Apnea, Experts Warn

About Half of Breast Cancer Survivors Seek Help for Sexual Issues

After Childhood Cancer, Sexual Dysfunction More Common in Women

Study: Antidepressant Lurasidone Has Fewer Sexual Side Effects

For Women, Placebo Effect Might Explain Improvement in Sexual Function

Childhood Sexual Abuse Linked to Sexual Problems in Women

Inhibition May Hinder Women’s Orgasms

PTSD Linked to Sexual Problems in Midlife Women

Low Desire Common in Midlife Women

For Breast Cancer Survivors, Sexual Concerns May Last Years

Poor Health and Lack of Communication Related to Low Sexual Interest, Study Says

Study Addresses Psychological Aspects of Female Sexual Problems

Body Image, Binge Eating, and Sexual Dysfunction in Women

Can Disclosing a Sexual Assault Help a Woman’s Sexual Functioning?

Women’s Sexuality Affected by Body Image and Relationship Quality, Study Says

Love, Sex, and Antidepressants
Exercise Helps Women With Antidepressant-Induced Sexual Side Effects
Sex Health Blog

Is It “Normal” for Libido to Vary Over Time?

HSDD: I Have No Sexual Desire, What Can I Do About It?

What Are Some Ways a Person Can Enhance Sexual Desire?

Enlarged Prostate Treatment and Your Sex Life

Female Cancer Survivors and Sex Health Issues
Did You Know?

Mindfulness Meditation May Reduce Sexual Stress

Veterans Often Face Further Sexual Difficulties after Military Sexual Trauma

Antidepressant Trintellix Has Fewer Sexual Side Effects, Study Finds

For Women, Meditation Could Have Sexual Benefits
_small.jpg)
A Third of Cervical Cancer Survivors Feel Sexual Distress

Sexual problems – such as low desire, poor arousal, and orgasm difficulties - are common side effects of some antidepressants. However, patients experiencing these effects may have a new alternative.
The U.S. Food and Drug Administration (FDA) has approved new labelling for a drug called Trintellix (vortioxetine), which may relieve depression symptoms with fewer sexual side effects.
Trintellix is prescribed to adults with major depressive disorder (MDD).
Researchers conducted an 8-week trial involving 447 patients who had been managing MDD with one of the following selective serotonin reuptake inhibitors (SSRIs): citalopram, paroxetine, or sertraline. The participants were also experiencing sexual side effects from their medication.
For the study, the participants switched their medication to either Trintellix or escitalopram. They also completed a sexual function assessment questionnaire at the start of the study and again eight weeks later.
When researchers analyzed the data, they found that the patients who took Tintrellix had better scores on the questionnaire. This meant that their sexual function improved over the study period.
In addition, the patients’ improvements with depression were maintained.
"Sexual dysfunction is one of the most common and bothersome side effects patients with depression struggle with when prescribed an SSRI," said lead investigator Dr. Anita Clayton in press statement.
She added, "We designed the study to specifically look at these troublesome side effects. Changing to a medication with potentially fewer sexual side effects, while not losing progress in treating depression, provides an important option for patients with depression."
Resources
Healio.com
“Expanded label shows Trintellix effective for SSRI-emergent sexual dysfunction”
(October 25, 2018)
https://www.healio.com/psychiatry/depression/news/online/%7Be4fb8ffd-4fa1-402b-a770-a231ad32f88d%7D/expanded-label-shows-trintellix-effective-for-ssri-emergent-sexual-dysfunction
MD Magazine
Rossi, Krista
“Label Update Shows Vortioxetine as Effective for Treatment-Emergent Sexual Dysfunction”
(October 22, 2018)
https://www.mdmag.com/medical-news/label-update-shows-vortioxetine-effective-treatmentemergent-sexual-dysfunction
MPR
Han, Da Hee, PharmD
“Vortioxetine Beats Escitalopram in Improving SSRI-Induced Sexual Dysfunction”
(October 22, 2018)
https://www.empr.com/news/trintellix-ssri-sexual-dysfunction-escitalopram-lexapro-study-labeling-update/article/809068/
PR Newswire
“New Data Added to TRINTELLIX® (vortioxetine) Labeling Demonstrated Superiority Over Escitalopram in Improving SSRI-Induced Sexual Dysfunction in Patients with Major Depressive Disorder”
(Press statement. October 22, 2018)
https://www.prnewswire.com/news-releases/new-data-added-to-trintellix-vortioxetine-labeling-demonstrated-superiority-over-escitalopram-in-improving-ssri-induced-sexual-dysfunction-in-patients-with-major-depressive-disorder-300734891.html
You may also be interested in...
Other Popular Articles

What Is Jelqing, and Does It Actually Work?
The term “jelqing” refers to a set of penis stretching exercises that some believe can make the penis bigger. Although the practice has gained attention and popularity in blogs and internet forums in recent years, there is no scientific evidence that it is an effective way to permanently increase the size of one’s penis. In fact, in some cases, jelqing may actually cause damage to the penis, so it is a good idea to get all the facts before setting off to try it.

What Is Sensate Focus and How Does It Work?
Sensate focus is a technique used to improve intimacy and communication between partners around sex, reduce sexual performance anxiety, and shift away from ingrained, goal-oriented sexual patterns that may not be serving a couple.

What Is the Average Penis Size?
If you have ever wondered how your penis compares to others in terms of size, you are not alone. Many men are curious to know how their penises stack up compared to the average. Unfortunately, general curiosity can sometimes give way to full-on obsession and anxiety about penis size. This can be an unhealthy and often unnecessary fixation, especially because most men who think their penises are too small have perfectly normal-sized penises.

Can Sex Reduce Menstrual Cramps?
The SMSNA periodically receives and publishes ‘guest editorials.’ The current article was submitted by Mia Barnes, a freelance writer and researcher who specializes in women's health, wellness, and healthy living. She is the Founder and Editor-in-Chief of Body+Mind Magazine.
Having sex while you experience menstrual cramps is healthy and can provide significant benefits. While it might not be the first activity that comes to mind when your PMS or period cramping begins, many people enjoy sex to reduce menstrual cramps, experience increased pleasure and benefit from other advantages. Learn more about having sex while menstrual cramps are happening and how it can help your body.

What Is Edging and Why Do People Do It?
Edging is the practice of stopping sexual stimulation before reaching orgasm to prolong a sexual experience. The term stems from the concept of approaching the metaphorical “edge” of orgasm but stopping before going over the edge.

The Effect of Regular Aerobic Exercise on Erectile Function
Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual activity. As men get older, their erectile functioning may naturally decline due to changes in testosterone levels, cardiovascular functioning, and the potential development of other chronic medical conditions that become more common with age.