Can Sleep Apnea Affect Sexual Function?

Can Sleep Apnea Affect Sexual Function?

Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated interruptions in breathing during sleep due to airway blockage. Affecting about 5 – 20% of adults, OSA has been linked to poor sleep quality, fatigue, and various health issues, including sexual dysfunction. Studies have examined connections between OSA and both male and female sexual dysfunction, suggesting that untreated OSA may contribute to reduced sexual health and satisfaction.

How OSA Affects Sexual Function

For men, OSA is associated with erectile dysfunction (ED), which is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. OSA-related ED is believed to stem from several biological factors. Frequent episodes of low oxygen, or “intermittent hypoxia,” during sleep may damage blood vessels and lower nitric oxide (NO) production, a molecule essential for blood flow to the genitals. Additionally, hormonal disruptions, such as lower testosterone levels in men with OSA, may contribute to diminished libido and erectile issues.

For women, the impact of OSA on sexual function is less studied, but available research suggests potential effects on desire, arousal, and lubrication. Women with OSA may experience hormonal changes that lower estrogen and progesterone levels, potentially reducing sexual arousal and satisfaction. Psychological symptoms, such as increased anxiety or depression related to poor sleep, may also contribute to these effects.

Treatment and Sexual Function Improvement

Continuous positive airway pressure (CPAP), the primary treatment for OSA, has shown promising results in improving sexual function in men. CPAP helps maintain open airways during sleep, reducing the effects of hypoxia and improving sleep quality. Some studies have reported that men with ED experienced up to a 40% improvement in erectile function after starting CPAP treatment. Although data on women’s sexual improvement with CPAP is limited, the treatment could potentially enhance sexual function by stabilizing hormones and reducing fatigue.

For those who prefer alternatives to CPAP, oral appliances that prevent airway collapse may be another option. These devices, similar to sports mouthguards, help keep the tongue and soft palate in place to maintain airway openness. Studies have shown that these appliances can also reduce some of the sexual dysfunction symptoms related to OSA.

Conflicting Evidence and Other Factors

Not all research supports a direct link between OSA and sexual dysfunction. Some studies suggest that other health factors, like age, obesity, and lifestyle choices, play more significant roles in sexual health than OSA alone. Additionally, while intermittent hypoxia is thought to impair sexual function, more studies are needed to determine if this effect is directly tied to OSA or results from other overlapping conditions, such as cardiovascular disease or diabetes.

Conclusion

While further research is necessary, existing studies highlight that OSA may negatively impact sexual function in both men and women, particularly if left untreated. CPAP and other treatments that improve sleep quality and reduce hypoxia have been shown to benefit sexual function, especially in men with ED. Addressing OSA not only improves overall health but may also enhance sexual well-being and quality of life.


References:

Cantone, E., Massanova, M., Crocetto, F., Barone, B., Esposito, F., Arcaniolo, D., Corlianò, F., Romano, L., Motta, G., & Celia, A. (2022). The relationship between obstructive sleep apnoea and erectile dysfunction: An underdiagnosed link? A prospective cross-sectional study. Andrologia54(9), e14504. https://doi.org/10.1111/and.14504

Gonçalves, M. A., Guilleminault, C., Ramos, E., Palha, A., & Paiva, T. (2005). Erectile dysfunction, obstructive sleep apnea syndrome, and nasal CPAP treatment. Sleep Medicine, 6(4), 333–339. https://doi.org/10.1016/j.sleep.2005.03.001

Gu, Y., Wu, C., Qin, F., & Yuan, J. (2022). Erectile Dysfunction and Obstructive Sleep Apnea: A Review. Frontiers in psychiatry13, 766639. https://doi.org/10.3389/fpsyt.2022.766639

Köseoğlu, N., Köseoğlu, H., Itil, O., Öztura, İ., Baklan, B., Ikiz, A. O., & Esen, A. A. (2007). Sexual function status in women with obstructive sleep apnea syndrome. The Journal of Sexual Medicine, 4(5), 1352–1357. https://doi.org/10.1111/j.1743-6109.2006.00302.x

Liu, L., Kang, R., Zhao, S., Zhang, T., Zhu, W., Li, E., Li, F., Wan, S., & Zhao, Z. (2015). Sexual dysfunction in patients with obstructive sleep apnea: A systematic review and meta-analysis. The Journal of Sexual Medicine, 12(10), 1992–2003. https://doi.org/10.1111/jsm.12983

Martínez Vázquez, S., Hernández Martínez, A., Peinado Molina, R. A., & Martínez Galiano, J. M. (2023). Association between sexual function in women and sleep quality. Frontiers in medicine10, 1196540. https://doi.org/10.3389/fmed.2023.1196540

Ng, J. H., & Yow, M. (2019). Oral Appliances in the Management of Obstructive Sleep Apnea. Sleep medicine clinics14(1), 109–118. https://doi.org/10.1016/j.jsmc.2018.10.012

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