What Are the Potential Side Effects of Erectile Dysfunction Medications, and Are There Alternative Treatments?
Erectile dysfunction (ED), or the inability to get and maintain an erection long enough for satisfactory sexual activity, is a common condition that affects men around the world. This condition can contribute to personal distress, relationship issues, and/or mental health problems for those who struggle with it.
Fortunately, there are effective oral medications available to treat ED, such as Viagra (sildenafil), Cialis (tadalafil), Levitra and Staxyn (vardenafil), and Stendra (avanafil). These medications are known as phosphodiesterase 5 (PDE5) inhibitors, and they can provide significant relief to individuals who take them.
Nevertheless, PDE5 inhibitors may also come with potential side effects. The following are some possible side effects of oral ED medications:
- Headaches: One of the most common side effects of PDE5 inhibitors is headaches. These can range from mild to severe and may occur shortly after taking the medication.
- Flushing of the skin: Some people experience facial flushing or redness in the face and neck, often described as a warm sensation. This is due to the medication’s effect of dilating blood vessels throughout the body.
- Digestive issues: Oral ED medications can lead to mild digestive problems, including indigestion, stomach discomfort, and diarrhea.
- Nasal congestion: A stuffy or runny nose can also occur as a result of taking these medications. It is usually a minor inconvenience.
- Muscle aches: Some types of PDE5 inhibitors can cause muscle aches or soreness.
- Vision changes: In rare cases, ED medications have been linked to vision changes, such as blurred vision, sensitivity to light, or a temporary bluish tint. While seeing a temporary bluish tint is not a medical emergency, if any of the other symptoms occur, seek immediate medical attention.
- Priapism: Also rare, priapism, a painful and prolonged erection lasting more than four hours, is a serious side effect that requires immediate medical attention. Failure to treat priapism promptly can lead to permanent damage to the penis.
- Interactions with other medications: If you are planning to take oral ED medications, it is crucial to inform your health care provider of all medications you are taking. PDE5 inhibitors can interact poorly with certain drugs, particularly those containing nitrates.
If you and your health care provider determine that oral ED medications may not be right for you, (particularly if they interact with other medications), there are alternative treatments for ED available.
Firstly, lifestyle changes, such as regular exercise, a balanced diet, maintaining a healthy weight, quitting smoking, and reducing stress can support healthy erectile functioning. This is because these changes promote good overall cardiovascular health, which is closely linked to erectile function.
For some men, ED has psychological causes. Counseling or psychotherapy, such as cognitive-behavioral therapy (CBT), can help address performance anxiety or relationship issues contributing to ED.
Alternatively, vacuum erection devices are external devices that create a vacuum around the penis, drawing blood into it and facilitating an erection. Then, a constriction band can be used to keep the blood in the penis and maintain the erection. These devices are a safe and effective alternative to oral ED medications for some men.
Intracavernosal injections involve directly injecting a medication into the penis that relaxes the blood vessels and increases blood flow to induce an erection. Additionally, intraurethral suppositories and topical agents such as the FDA-approved Eroxon can be used to create erections.
Low-intensity shockwave therapy is a relatively new and potentially promising treatment for ED. It works by using low-energy shockwaves to improve blood flow and stimulate the growth of new blood vessels in the penis, but there is still debate within the sexual medicine community around its effectiveness.
Lastly, surgically implanted inflatable penile prostheses (IPPs) or malleable prostheses can provide a lasting solution to ED. IPPs are discreet and can be inflated to create an erection when desired, while malleable devices can be maneuvered into position away from the body to create an erection.
For more information on this topic, please read these publications from the ISSM Journals: The Journal of Sexual Medicine, Sexual Medicine Reviews, and Sexual Medicine Open Access:
References:
Lue, T.F. (2000). Erectile dysfunction. New England journal of medicine, 342(24), 1802-1813. DOI: 10.1056/NEJM200006153422407
Mayo Clinic. (2023, June 24). Erectile dysfunction: Viagra and other oral medications. https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/in-depth/erectile-dysfunction/art-20047821
You may also be interested in...
Did You Know?
Penile Implants From a Partner's Perspective
November 2, 2021SMSNA
Review of SMSNA Position Statement on Restorative Therapies
October 22, 2021Did You Know?
Penile Implants for Erectile Dysfunction: A Q&A With an Implant Specialist
September 14, 2021SMSNA
Findings on Location and Severity of Pain After Inflatable Penile Prosthesis Surgery
October 21, 2021Did You Know?
What Is Jelqing, and Does It Actually Work?
August 17, 2021Blog
The Role of the Mind in Erections and Erectile Dysfunction
May 27, 2021Did You Know?
A Non-Medicated Gel to Treat Erectile Dysfunction: Snake Oil or the Real Deal?
May 25, 2021Did You Know?
Alcohol and Temporary Erectile Dysfunction
February 2, 2021Blog
An Overview of Hard Flaccid Syndrome
March 2, 2021Other Popular Articles
What Is Jelqing, and Does It Actually Work?
The term “jelqing” refers to a set of penis stretching exercises that some believe can make the penis bigger. Although the practice has gained attention and popularity in blogs and internet forums in recent years, there is no scientific evidence that it is an effective way to permanently increase the size of one’s penis. In fact, in some cases, jelqing may actually cause damage to the penis, so it is a good idea to get all the facts before setting off to try it.
What Is Sensate Focus and How Does It Work?
Sensate focus is a technique used to improve intimacy and communication between partners around sex, reduce sexual performance anxiety, and shift away from ingrained, goal-oriented sexual patterns that may not be serving a couple.
What Is the Average Penis Size?
If you have ever wondered how your penis compares to others in terms of size, you are not alone. Many men are curious to know how their penises stack up compared to the average. Unfortunately, general curiosity can sometimes give way to full-on obsession and anxiety about penis size. This can be an unhealthy and often unnecessary fixation, especially because most men who think their penises are too small have perfectly normal-sized penises.
What Is Edging and Why Do People Do It?
Edging is the practice of stopping sexual stimulation before reaching orgasm to prolong a sexual experience. The term stems from the concept of approaching the metaphorical “edge” of orgasm but stopping before going over the edge.
The Sex-Positivity Movement: What it Means to Be Sex-Positive
You may have heard references to “being sex-positive” or “the sex-positivity movement” in popular culture. Various celebrities have brought attention to this movement by speaking out about their beliefs and personal experiences regarding sexuality, sexual health, body positivity, “slut-shaming,” and sexual assault.
Can Sex Reduce Menstrual Cramps?
The SMSNA periodically receives and publishes ‘guest editorials.’ The current article was submitted by Mia Barnes, a freelance writer and researcher who specializes in women's health, wellness, and healthy living. She is the Founder and Editor-in-Chief of Body+Mind Magazine.
Having sex while you experience menstrual cramps is healthy and can provide significant benefits. While it might not be the first activity that comes to mind when your PMS or period cramping begins, many people enjoy sex to reduce menstrual cramps, experience increased pleasure and benefit from other advantages. Learn more about having sex while menstrual cramps are happening and how it can help your body.
