At the second day of the 26th SMSNA Annual Fall Scientific Meeting, Dr. Bradley Gill provided an overview of current office-based, minimally invasive surgical therapies for benign prostatic hyperplasia (BPH), as supported by AUA guidelines.

Most approaches are tailored to prostate size, and patient goals  related to sexual function and fertility should also be considered. Dr. Gill emphasized one key phrase: “matching the right procedure to the right prostate and the right patient,” noting that not all BPH treatments and patients are created equal. Diagnosis should include ultrasound or CT scans, along with urodynamic tests when necessary.

Depending on the size of the patient's prostate and their individual goals, consider the following in-office treatments if the patient is comfortable with them: implantable temporary nitinol devices, UroLift, water vapor thermal therapy, and drug-coated balloon dilation. However, providers should be mindful of AUA-specific indications for each therapy.

At the second day of the 26th SMSNA Annual Fall Scientific Meeting, Dr. Brian Willoughby shared his research on pornography and its influence on mental health, along with his thoughts on the future of pornography.

Most research shows that pornography use peaks in young adulthood and declines with age, and that nearly twice as many men as women consume pornography. Other studies report that around half of surveyed couples use pornography together.

Dr. Willoughby discussed how the frequency of pornography consumption can affect mental health and relationships. More frequent use is associated with increasingly negative views toward sexual activity and partnerships. However, he noted an important caveat: the content and nature of the pornography consumed may contribute to more severe mental health outcomes. Generally speaking, there are few instances of compulsive sexual behavior such as this, which may involve more violent content and behaviors.

According to Dr. Willoughby, the future of pornography appears to be moving toward AI and deepfakes, which may have a greater impact on relationships and mental health, particularly depression and anxiety, than traditional pornography. Deepfakes allow for customized content with the face of a desired sexual partner, and AI companions are customizable in terms of personality and design, potentially making it more difficult for individuals to feel fully satisfied with real-life romantic partners.

At the first day of the 26th SMSNA Annual Fall Scientific Meeting, Dr. Eliza Burr discussed the effects of GLP-1 and GLP-1/GIP receptor agonists on female sexual function, and in respect to age group in two subsequent studies.

Dr. Burr’s first study revealed that a quarter of participants reported changes in sexual function, with half of those reports experiencing a distressing decrease in sexuaal function. Specifically, the results showed a statistically significant decrease in the domains of desire and arousal.

The second study revealed significant decreases in sexual function in the 31–40-year-old age group, with fewer reports of sexual dysfunction as age increased. This trend appears to correlate with hormonal changes across pre-, peri-, and postmenopausal groups. Given that the decrease in sexual function was consistent across age groups in women taking GLP-1 and GLP-1/GIP receptor agonists, Dr. Burr posits that this may indicate a baseline level of sexual function among women on these medications.

Dr. Burr recommends further and more rigorous research into the effects of GLP-1 and GLP-1/GIP receptor agonists on female sexual function, as current findings remain inconsistent.

At the first day of the 26th Annual Fall Scientific Meeting, Dr. Jessica Schardein discussed penile disorders in male non-cancer patients through a biopsychosocial lens, emphasizing the importance of multidisciplinary collaboration between clinicians and mental health professionals.

Depression, anxiety, and relationship conflicts may be primary or secondary contributors to erectile dysfunction, and can affect treatment outcomes for multiple disorders. Dr. Schardein emphasizes that approaches targeting both the mind and body may increase the likelihood of treatment success, combining medication and sexual health-specific therapy.

Diagnostic guildelines often include direction for reffering patients to mental health professionals based on the level of distress the patient is experiencing due to erectile dysfunction, Peyronie’s disease, or other conditions. However, Dr. Schardein recommends that all patients with sexual dysfunction are referred to a mental health professional, as this may help reduce distress and support better treatment adherence.

While there is a benefit to discussing treatment in therapy, Dr. Schardein emphasizes four main points to remember: recognize loss, give space for grief, identify strengths, and help patients reframe negative thinking.

At the first day of the 26th SMSNA Annual Fall Scientific Meeting, Dr. Aaron Miller briefly discussed the implications of biofilms on implantable medical devices.

Dr. Miller's research discovered that the origin of infectious biofilms was found to come from the host, as the subcutaneous tissue's biofilm was identical to the device's biofilm. This points to an obstacle in infection prevention: the influence of the patient's microbiome.

Comparing device materials, Dr. Miller found that bacterial count was influenced by the device manufacturer and the material used, with titanium offering the lowest risk of bacterial growth. Antibiotic use increased the abundance of known pathogens, leading to an increased risk of infection. Moving away from broad-spectrum antibiotics and creating patient-specific combinations may be useful in the future.

With further research and development, Dr. Miller believes the introduction of new materials and quorum-sensing inhibitors may be beneficial in reducing the risk of infections with implantable medical devices.

Pelvic floor muscles (PFM) have a distinct connection to female sexual dysfunction (FSD). Because PFMs surround the female reproductive organs, they play a large part in FSD like dyspareunia, vulvodynia, vestibulodynia, and more. Weak PFMs may lead to a feeling of looseness in the vagina and may contribute toward pelvic organ prolapse (POP), where the pelvic organs begin to fall out through the vagina. Additionally, PFMs being too strong or tight may contribute toward pelvic and vaginal pain disorders.

"Whether it be by helping to improve one's intimacy with their partner, helping to conceive, or improving energy and overall health and well-being, every day is truly rewarding."

September's Member of the Month is Kristy Mardis, NP! You can learn more about Kristy and her work here!

A large number of patients with sexual dysfunction may also have neurological disorders that play a direct role in their sexual functioning. Sexual dysfunction and neurologic disorders are comorbidities that have a negative effect on overall quality of life, and it is recommended that they be treated in tandem. This article aims to briefly cover a variety of neurologic disorders and their direct effects on sexual dysfunction.

Since the 1940s, there have been conflicting theories and conclusions surrounding testosterone replacement therapy (TRT), and whether or not it is safe for hypogonadal men with or without a history of radically treated prostate cancer (PCa). This article will go over some international guidelines and recent research on how to approach TRT in hypogonadal PCa patients.

Dealing with breast cancer is not easy, for patients, families, and care providers alike. Even beyond the emotional and physical toll of cancer treatment, there are unacknowledged effects that every patient may face. Breast cancer survivors represent over 40% of all cancer survivors. Of these, around 50% report experiencing some sort of sexual difficulty, with 45% reporting sexual pain.